Clamp-end valve body data sheet

NovaSeptic range overview

NovaSeptic nomenclature and configurator

NovAseptic valves are renowned for their performance, reliability, longevity and ease of maintenance. The design and development of each component draw on more than 35 years of experience focused on aseptic design. NovAseptic valves comply with the design qualification criteria established by current GMP (Good Manufacturing Practice) for aseptic processes. This is why we have chosen to describe these valves as aseptic by design.

The range was originally developed to address the challenges of tank bottom valves: no dead zone, self-draining and fully drainable, low pressure drop, the smallest possible weld-in flange diameter to bring the agitator closer to the centre of the tank, very simple maintenance since this valve is generally not accessible, diaphragms suited to the materials of pharmaceutical process tanks, and compact or right-angle actuators. This design was then extended to 2-way or 3-way valves, offering an aseptic alternative to the in-line diaphragm valve.

The range is modular. NovAseptic valve bodies are available in imperial sizes, from 1/2″ to 3″. On each body configuration with the same process connection diameter, all diaphragms, actuators and accessories of that same size can be fitted.

Aseptic tank bottom valve with two outlets, no dead zone, 1/2″ to 3″

NovAseptic type 45 valve body, tank bottom configuration with two outlets. Aseptic design with no dead zone, drainable, low pressure drop. Electropolished body with Ra below 0.38 µm, several stainless steel grades depending on the process. Process pressure -1 to 7 bar. Imperial sizes 1/2″ to 3″. Straight or angled outlet, weld or tri-clamp connection. EN 10204-3.1 certificate, ATEX version available. Category: tank bottom valves.

The valve designed for the tank bottom

Type 45 takes the tank bottom design of type 44 with two outlets, to feed two separate lines from the same tank low point, without multiplying tappings or dead volumes.

The two outlets share the same drainable body and the same compact flange. Each line retains the absence of dead zones and the self-draining capability that define the tank bottom valve.

This configuration avoids adding a second in-line valve downstream, which reduces the number of points to qualify and clean on the tank bottom.

Body and specifications

The body is available in several grades depending on the aggressiveness of the process, with a straight or angled outlet, and a weld or tri-clamp connection.

Compatible diaphragms

The type 45 body accepts the four diaphragms in the range, all FDA and USP Class VI, to be chosen according to the fluid and operating temperature.

The type 25 PTFE diaphragm requires the type 84 interface. Diaphragm selection follows chemical compatibility and temperature, as for any product-contact component.

Compatible actuators and accessories

The type 45 body can be operated by all actuators in the range, from manual to ATEX pneumatic, to be chosen according to the control mode, accessibility and zone classification.

Frequently asked questions

Why a dedicated tank bottom valve rather than an in-line valve?

Because a tank bottom requires the absence of dead zones, complete drainage and a compact flange to bring the agitator closer. An in-line diaphragm valve repurposed for the tank bottom meets none of these three requirements.

Which body grade should I choose?

316L covers most pharmaceutical processes. Grades 1.4435 BN2, 904L, AL6XN and Hastelloy C22 meet the needs of more aggressive or more chlorinated fluids, in order of increasing corrosion resistance.

Which diaphragm and which actuator?

All diaphragms and actuators of the same diameter can be fitted on this body. The diaphragm is chosen based on the fluid and temperature, the actuator based on the control mode and zone classification. See the dedicated data sheets.

Straight or angled outlet?

Depending on the line geometry. Straight BW outlet for an in-line exit, 45° or 90° angled to change direction without adding a separate elbow, which limits dead volumes.

Clamp-end valve body data sheet

NovaSeptic range overview

NovaSeptic nomenclature and configurator

NovAseptic valves are renowned for their performance, reliability, longevity and ease of maintenance. The design and development of each component draw on more than 35 years of experience focused on aseptic design. NovAseptic valves comply with the design qualification criteria established by current GMP (Good Manufacturing Practice) for aseptic processes. This is why we have chosen to describe these valves as aseptic by design.

The range was originally developed to address the challenges of tank bottom valves: no dead zone, self-draining and fully drainable, low pressure drop, the smallest possible weld-in flange diameter to bring the agitator closer to the centre of the tank, very simple maintenance since this valve is generally not accessible, diaphragms suited to the materials of pharmaceutical process tanks, and compact or right-angle actuators. This design was then extended to 2-way or 3-way valves, offering an aseptic alternative to the in-line diaphragm valve.

The range is modular. NovAseptic valve bodies are available in imperial sizes, from 1/2″ to 3″. On each body configuration with the same process connection diameter, all diaphragms, actuators and accessories of that same size can be fitted.

Tank bottom valve with integrated clean-in-place point, 1/2″ to 3″

NovAseptic type 46 valve body, tank bottom configuration with CIP valve. Aseptic design with no dead zone, drainable, low pressure drop. Electropolished body with Ra below 0.38 µm, several stainless steel grades depending on the process. Process pressure -1 to 7 bar. Imperial sizes 1/2″ to 3″. Straight or angled outlet, weld or tri-clamp connection. EN 10204-3.1 certificate, ATEX version available. Category: tank bottom valves.

The valve designed for the tank bottom

Type 46 integrates a clean-in-place valve into the tank bottom body. The dedicated CIP point allows the cleaning solution to be injected as close as possible to the tank bottom, where retention is most critical.

Integrating the CIP valve into the body eliminates the add-on cleaning tapping and the dead volume it creates. Cleaning reaches the low point of the tank without any shadow zone.

This is the configuration chosen when the CIP procedure must be qualified right down to the tank bottom, in demanding sterile processes.

Body and specifications

The body is available in several grades depending on the aggressiveness of the process, with a straight or angled outlet, and a weld or tri-clamp connection.

Compatible diaphragms

The type 46 body accepts the four diaphragms in the range, all FDA and USP Class VI, to be chosen according to the fluid and operating temperature.

The type 25 PTFE diaphragm requires the type 84 interface. Diaphragm selection follows chemical compatibility and temperature, as for any product-contact component.

Compatible actuators and accessories

The type 46 body can be operated by all actuators in the range, from manual to ATEX pneumatic, to be chosen according to the control mode, accessibility and zone classification.

Frequently asked questions

Why a dedicated tank bottom valve rather than an in-line valve?

Because a tank bottom requires the absence of dead zones, complete drainage and a compact flange to bring the agitator closer. An in-line diaphragm valve repurposed for the tank bottom meets none of these three requirements.

Which body grade should I choose?

316L covers most pharmaceutical processes. Grades 1.4435 BN2, 904L, AL6XN and Hastelloy C22 meet the needs of more aggressive or more chlorinated fluids, in order of increasing corrosion resistance.

Which diaphragm and which actuator?

All diaphragms and actuators of the same diameter can be fitted on this body. The diaphragm is chosen based on the fluid and temperature, the actuator based on the control mode and zone classification. See the dedicated data sheets.

Straight or angled outlet?

Depending on the line geometry. Straight BW outlet for an in-line exit, 45° or 90° angled to change direction without adding a separate elbow, which limits dead volumes.

NovaSeptic range overview

NovaSeptic nomenclature and configurator

NovAseptic valves are renowned for their performance, reliability, longevity and ease of maintenance. The design and development of each component draw on more than 35 years of experience focused on aseptic design. NovAseptic valves comply with the design qualification criteria established by current GMP (Good Manufacturing Practice) for aseptic processes. This is why we have chosen to describe these valves as aseptic by design.

The range was originally developed to address the challenges of tank bottom valves: no dead zone, self-draining and fully drainable, low pressure drop, the smallest possible weld-in flange diameter to bring the agitator closer to the centre of the tank, very simple maintenance since this valve is generally not accessible, diaphragms suited to the materials of pharmaceutical process tanks, and compact or right-angle actuators. This design was then extended to 2-way or 3-way valves, offering an aseptic alternative to the in-line diaphragm valve.

The range is modular. NovAseptic valve bodies are available in imperial sizes, from 1/2″ to 3″. On each body configuration with the same process connection diameter, all diaphragms, actuators and accessories of that same size can be fitted.

Aseptic tank bottom valve, no dead zone, fully drainable, 1/2″ to 3″

NovAseptic type 44 valve body, tank bottom configuration with one outlet. Aseptic design with no dead zone, drainable, low pressure drop. Electropolished body with Ra below 0.38 µm, several stainless steel grades depending on the process. Process pressure -1 to 7 bar. Imperial sizes 1/2″ to 3″. Straight or angled outlet, weld or tri-clamp connection. EN 10204-3.1 certificate, ATEX version available. Category: tank bottom valves.

The valve designed for the tank bottom

Type 44, with one outlet, is the basic tank bottom configuration. The success of the NovAseptic tank bottom valve is well established: it is widely recommended and used on pharmaceutical process tanks.

The absence of dead zones and complete drainage govern the asepsis of a tank bottom. Type 44 is designed so that no low point retains liquid, with the valve emptying completely by gravity.

The reduced weld-in flange diameter allows the agitator to be brought closer to the centre of the tank, improving mixing homogeneity, a compromise that repurposed in-line valves cannot achieve.

Body and specifications

The body is available in several grades depending on the aggressiveness of the process, with a straight or angled outlet, and a weld or tri-clamp connection.

Compatible diaphragms

The type 44 body accepts the four diaphragms in the range, all FDA and USP Class VI, to be chosen according to the fluid and operating temperature.

The type 25 PTFE diaphragm requires the type 84 interface. Diaphragm selection follows chemical compatibility and temperature, as for any product-contact component.

Compatible actuators and accessories

The type 44 body can be operated by all actuators in the range, from manual to ATEX pneumatic, to be chosen according to the control mode, accessibility and zone classification.

Frequently asked questions

Why a dedicated tank bottom valve rather than an in-line valve?

Because a tank bottom requires the absence of dead zones, complete drainage and a compact flange to bring the agitator closer. An in-line diaphragm valve repurposed for the tank bottom meets none of these three requirements.

Which body grade should I choose?

316L covers most pharmaceutical processes. Grades 1.4435 BN2, 904L, AL6XN and Hastelloy C22 meet the needs of more aggressive or more chlorinated fluids, in order of increasing corrosion resistance.

Which diaphragm and which actuator?

All diaphragms and actuators of the same diameter can be fitted on this body. The diaphragm is chosen based on the fluid and temperature, the actuator based on the control mode and zone classification. See the dedicated data sheets.

Straight or angled outlet?

Depending on the line geometry. Straight BW outlet for an in-line exit, 45° or 90° angled to change direction without adding a separate elbow, which limits dead volumes.